Picture of  David Janz

David Janz Professor, Department of Veterinary Biomedical Sciences

Research Area(s)

  • Interactions between physiological control and environmental alteration of developmental and reproductive processes in vertebrates

Academic Credentials

  • BSc, Simon Fraser University
  • MSc, Trent University
  • PhD, University of British Columbia
  • Post-Doctoral training, University of Guelph

Research Interests

Dr. Janz investigates interactions between physiological control and environmental alteration of developmental and reproductive processes in vertebrates.

The goal is to investigate relationships between biological responses at the molecular and cellular levels with those occurring at the organ, organism and population levels in animals exposed to environmental stressors. This is achieved by combining physiological, cell biological, pharmacological and molecular biological approaches in the laboratory with ecological approaches in the field.

Dr. Janz's recent work has focused on developing non-invasive techniques to measure long-term stress in fish and wildlife species.

Publications

Recent Publications (for full list see https://orcid.org/0000-0002-1866-9787)

2019

Wilson AE, Fair PA, Carlson RI, Houde M, Cattet M, Bossart GD, Houser DS, *Janz DM, (2019). Environment, endocrinology, and biochemistry influence expression of stress proteins in bottlenose dolphins. Comparative Biochemistry and Physiology Part D: Genomics and Proteomics, 32: 100613.   https://doi.org/10.1016/j.cbd.2019.100613

Graves SD, Liber K, Palace V, Hecker M, Doig LE, *Janz DM, (2019). Effects of selenium on benthic macroinvertebrates and fathead minnow (Pimephales promelas) in a boreal lake ecosystem. Ecotoxicology and Environmental Safety, 182: 10934. https://doi.org/10.1016/j.ecoenv.2019.06.037

Graves SD, Liber K, Palace V, Hecker M, Doig LE, *Janz DM, (2019). Distribution of experimentally added selenium in a boreal lake ecosystem. Environmental Toxicology and Chemistry, 38: 1954-1966. https://doi.org/10.1002/etc.4508

Gerhart AK, *Janz DM, (2019). Toxicity of aqueous L-selenomethionine and tert-butyl hydroperoxide exposure to zebrafish (Danio rerio) embryos following tert-butyl hydroquinone treatment. Toxics, 7: 44. https://doi.org/10.3390/toxics7030044

Lane T, Green D, Bluhm K, Raes K, Janz DM, Liber K, Hecker M, (2019). In ovo exposure of fathead minnow (Pimephales promelas) to selenomethionine via maternal transfer and embryo microinjection: A comparative study. Aquatic Toxicology, 216: 105299. https://doi.org/10.1016/j.aquatox.2019.105299

Markwart B, Liber K, Xie Y, Raes K, Hecker M, Janz DM, Doig LE, (2019). Selenium oxyanion bioconcentration in natural freshwater periphyton. Ecotoxicology and Environmental Safety, 180: 693-704. https://doi.org/10.1016/j.ecoenv.2019.05.004

Coogan SCP, Coops NC, Janz DM, Cattet MRL, Kearney SP, Stenhouse GB, Nielsen SE, (2019). Towards grizzly bear population recovery in a modern landscape. Journal of Applied Ecology, 56: 93-99. https://doi.org/10.1111/1365-2664.13259

Gerhart AK, Hecker M, *Janz DM, (2019). Toxicity of aqueous L-selenomethionine exposure to early life-stages of the fathead minnow (Pimephales promelas). Bulletin of Environmental Contamination and Toxicology, 102: 323-328. https://doi.org/10.1007/s00128-018-02537-2

Karpovich SA, Skinner JP, Kapronczai LA, Smith JA, *Janz DM, (2019). Examination of relationships between stable isotopes and cortisol concentrations along the length of phocid whiskers. Marine Mammal Science, 35: 395-415. https://doi.org/10.1111/mms.12546

Crill C, Janz DM, Kusch JM, Santymire RM, Heyer GP, Shury TK, Lane JE, (2019). Investigation of the utility of feces and hair as non-invasive measures of glucocorticoids in wild black-tailed prairie dogs (Cynomys ludovicianus). General and Comparative Endocrinology, 275: 15-24. https://doi.org/10.1016/j.ygcen.2019.02.003

2018

Pettem CM, Briens JM, Janz DM, Weber LP, (2018). Cardiometabolic response of juvenile rainbow trout exposed to dietary selenomethionine. Aquatic Toxicology, 198: 175-189. https://doi.org/10.1016/j.aquatox.2018.02.022

Cattet M, Stenhouse GB, Boulanger J, Janz DM, Kapronczai L, Swenson JE, Zedrosser A, (2018). Can concentrations of steroid hormones in brown bear hair reveal age class? Conservation Physiology, 6: https://doi.org/10.1093/conphys/coy001

2017

Pettem CM, Weber LP, *Janz DM, (2017). Cardiac and metabolic effects of dietary selenomethionine exposure in adult zebrafish. Toxicological Sciences, 159: 449-460. https://doi.org/10.1093/toxsci/kfx149

Demuth BS, Ferrari MCO, Weber LP, Janz DM, Chivers DP, (2017). Exposure to a contextually neutral stressor potentiates fear conditioning in juvenile rainbow trout, Oncorhynchus mykissHormones and Behavior, 94: 124-134. https://doi.org/10.1016/j.yhbeh.2017.07.002

Kroshko T, Kapronczai L, Cattet M, Macbeth BJ, Stenhouse GB, Obbard ME, *Janz DM, (2017). Comparison of methanol and isopropanol as wash solvents for determination of hair cortisol concentration in grizzly bears and polar bears. MethodsX, 4: 68-75. https://doi.org/10.1016/j.mex.2017.01.004

Cattet M, Stenhouse GB, Janz DM, Kapronczai L, Erlenbach JA, Jansen HT, Nelson OL, Robbins CT, Boulanger J, (2017). The quantification of reproductive hormones in the hair of captive adult brown bears and their application as indicators of sex and reproductive state. Conservation Physiology, 5: https://doi.org/10.1093/conphys/cox032

Sergiel A, Hobson KA, Janz DM, Cattet M, Selva N, Kapronczai L, Gryba C, Zedrosser A, (2017). Compatibility of preparatory procedures for the analysis of cortisol concentrations and stable isotope (d13C, d15N) ratios: A test on brown bear hair. Conservation Physiology, 5: https://doi.org/10.1093/conphys/cox021

Duran MC, Janz DM, Waldner CL, Campbell JR, Marques FJ, (2017). Hair cortisol concentration as a stress biomarker in horses: Associations with body location and surgical castration. Journal of Equine Veterinary Science, 55: 27-33. https://doi.org/10.1016/j.jevs.2017.03.220

Creutzinger KJ, Stookey J, Marfleet T, Campbell JR, Janz DM, Marques FJ, Seddon Y, (2017). An investigation of hair cortisol as a measure of long-term stress in beef cattle: Results from a castration study. Canadian Journal of Animal Science, 97: 499-509.  https://doi.org/10.1139/cjas-2016-0206

2016

Massé AJ, Muscatello JR, Hogan NS, *Janz DM, (2016). Tissue-specific selenium accumulation and toxicity in adult female Xenopus laevis chronically exposed to elevated dietary selenomethionine. Environmental Toxicology and Chemistry, 36: 1047-1055. https://doi.org/10.1002/etc.3627

Massé AJ, Muscatello JR, *Janz DM, (2016). Effects of elevated in ovo selenium exposure on late stage development of Xenopus laevis tadpoles. Bulletin of Environmental Contamination and Toxicology, 97: 463-468. https://doi.org/10.1007/s00128-016-1884-6

Thomas JK, *Janz DM, (2016). Embryo microinjection of selenomethionine reduces hatchability and modifies oxidant responsive gene expression in zebrafish. Scientific Reports, 6: https://doi.org/10.1038/srep26520

Carlson RI, Cattet MRL, Sarauer BL, Nielsen SE, Boulanger J, Stenhouse GB, *Janz DM, (2016). Development and application of an antibody-based protein microarray to assess physiological stress in grizzly bears (Ursus arctos). Conservation Physiology, 4: https://doi.org/10.1093/conphys/cow001

Mislan P, Derocher AE, St. Louis VL, Richardson E, Lunn NJ, Janz DM, (2016). Assessing stress in Western Hudson Bay polar bears using hair cortisol as a biomarker. Ecological Indicators, 71: 47-54. https://doi.org/10.1016/j.ecolind.2016.06.034

Green DJ, Duffy M, Janz DM, McCullum K, Carrière G, Jardine TD, (2016). Historical and contemporary patterns of mercury in a hydroelectric reservoir and downstream fishery: Concentration decline in water and fishes. Archives of Environmental Contamination and Toxicology, 71: 157-170. https://doi.org/10.1007/s00244-016-0287-3

Raine JC, Lallemand L, Pettem CM, Janz DM, (2016). Effects of chronic dietary selenomethionine exposure on the visual system of adult and F1 generation zebrafish (Danio rerio). Bulletin of Environmental Contamination and Toxicology, 97: 331-336. https://doi.org/10.1007/s00128-016-1849-9

Painter KJ, Janz DM, Jardine TD, (2016). Bioaccumulation of mercury in invertebrate food webs of Canadian Rocky Mountain streams. Freshwater Science, 35: 1248-1262. https://doi.org/10.1086/688897

Bishop CA, Trudeau S, Janz DM, Hughes KD, (2016). Contaminant concentrations and biomarkers in 21-day old herring gulls (Larux argentatus) and double-crested cormorants (Phalacrocorax auritus) from eastern Lake Ontario, and from Hamilton Harbour in western Lake Ontario in 1989 and 1990. Aquatic Ecosystem Health and Management, 19: 181-191. https://doi.org/10.1080/14634988.2016.1150020