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Western College of Veterinary Medicine

Research Area(s)

  • Reproductive biology

Academic Credentials

  • DVM, University of Saskatchewan
  • MS, University of Wisconsin
  • PhD, University of Wisconsin
  • Diplomate ACT, American College of Theriogenologists

Dr. Adams teaches veterinary anatomy in the veterinary curriculum and participates in team-taught graduate courses on:

  • Advanced Physiology and Endocrinology of Reproduction in Mammals
  • Advanced Bovine Reproduction
  • Bovine Reproductive Ultrasonography and Embryo Transfer
  • Research Techniques in Endocrinology and Reproduction

He is a team member of the course Biomedical Rounds that was awarded the Provost's Prize for Innovative Practice of Teaching and Learning, University of Saskatchewan (2008). Dr. Adams also consults on theriogenology cases admitted to the WCVM Veterinary Medical Centre.

Other Appointments

  • President, International Embryo Transfer Society (2014)
  • Chair, International Congress on Animal Reproduction (2012)
  • Chair, Reproductive Science and Medicine Group, University of Saskatchewan
  • Chair, Grant Selection Committee, Natural Sciences and Engineering Research Council (NSERC)
  • Executive, Biomedical Imaging and Therapy Beam Team, Canadian Light Source
  • Associate, Obstetrics and Gynecology, Royal University Hospital, University of Saskatchewan

Research Interests

Dr. Adams has broad interests in basic and applied aspects of reproductive science and medicine, and he is recognized internationally for his work on ovarian function.

He has published classic studies of ovarian follicle development, ovulation and fertility in several species including cattle, camelids, cervids and humans. Results of studies on ovarian function in women by Dr. Adams and co-workers at the University of Saskatchewan was cited as one of the top 100 scientific discoveries of the year by Discover Magazine.

Technical applications resulting from his work include:

  • ovarian synchronization and superstimulation
  • oocyte collection
  • in vitro embryo production and transfer in cattle and camelids
  • 2- and 3-dimensional ultrasonography
  • computer-assisted image analysis

Dr. Adams' current research focuses on 1) ovulation-inducing factor in seminal plasma, 2) the establishment of a germplasm biobank for Canada’s threatened Wood Bison, 3) novel aromatase inhibitor-based method of ovarian synchronization in animals, and 4) embryonic diapause in pinnipeds.

His discoveries on "The nerve of ovulation-inducing factor" and “World's first in-vitro bison calves born at University of Saskatchewan” have been publicized widely in the popular press.

Google Scholar Citation indices

All

Since 2016

Citations

16181

5336

h-index

67

39

i10-index

186

130

 

Research Awards & Accomplishments

  • International Embryo Technology Society Mentor of the Year Award 2016
  • Theriogenologist of the Year, American College of Theriogenologists 2014
  • University of Saskatchewan’s Distinguished Researcher Award.
  • SmithKline Beecham Award for Research Excellence.
  • Principal supervisor for 32 graduate students and postdoctoral fellows.
  • Held over 50 grants from federal, provincial and private sources including 25 continuous years of NSERC funding.
  • Authored over 200 peer-reviewed publications and has given more than 120 invited presentations including keynote addresses at national and international conferences.

Publications

  • Carrasco, R.A., Leonardi, C.E., Hutt, K., Singh, J., Adams, G.P.  2020.  Kisspeptin induces LH release and ovulation in an induced ovulator.  Biology of Reproduction, 103(1): 49-59.  https://www.doi.org/10.1093/biolre/ioaa051

  • Krause, A.R.T., Dias, F.C.F., Adams, G.P., Mapletoft, R.J., Singh, J.  2020.  Effect of dose and duration of FSH treatment on ovarian response in prepubertal calves.  Animal Reproduction Science, 219: 106471.  https://www.doi.org/10.1016/j.anireprosci.2020.106471

  • Leonardi, C.E.P., Dias, F.C.F., Adams, G.P., Araujo, E.R., Singh, J.  2020.  Kisspeptin induces ovulation in heifers under low plasma progesterone concentrations.  Theriogenology, 141: 26-34.  https://www.doi.org/10.1016/j.theriogenology.2019.08.033

  • Palomino, J.M., Mastromonaco, G.F., Cervantes, M.P., Mapletoft, R.J., Anzar, M., Adams, G.P.  2020.  Effect of season and superstimulatory treatment on in vivo and in vitro embryo production in wood bison (Bison bison athabascae).   Reproduction in Domestic Animals, 55(1): 54-63.  https://www.doi.org/10.1111/rda.13580

  • Yang, S.X., Adams, G.P., Palomino, J.M., Huanca, W.F., Lessard, C., Rajapaksha, K., Anzar, M.  2020.  Cryopreservation of bison semen without exogenous protein in extender and its fertility potential in vitro and in vivo following fixed-time artificial insemination.  Theriogenology, 152: 156-164.  https://www.doi.org/10.1016/j.theriogenology.2020.04.018

  • Zwiefelhofer, E.M., Davis, B.M., Adams, G.P.  2020.  Research and development of a silicone letrozole-releasing device to control reproduction in cattle.  Theriogenology, 146: 104-110.  https://www.doi.org/10.1016/j.theriogenology.2020.02.008

  • Zwiefelhofer, E.M., Mapletoft, R.J., Adams, G.P.  2020.  An attempt to potentiate the ovarian superstimulatory response in cattle by co-treatment with an aromatase inhibitor.  Theriogenology, 157: 1-6.  https://www.doi.org/10.1016/j.theriogenology.2020.07.019

  • Carrasco, R.A., Verhoef, J., Leonardi, C.E.P., Lanigan, E.E., Adams, G.P.  2019.  Bilateral thyroid follicular compact-cellular carcinoma in a llama.  Journal of Veterinary Diagnostic Investigation, 31(6): 913-916.  https://www.doi.org/10.1177/1040638719882734

  • Caunce, S.L., Dadarwal, D., Adams, G.P., Brar, P., Singh, J.  2019.  An objective volumetric method for assessment of ovarian follicular and luteal vascular flow using colour Doppler ultrasonography.  Theriogenology, 138: 66-76.  https://www.doi.org/10.1016/j.theriogenology.2019.06.039

  • Ratto, M.H., Berland, M., Silva, M.E., Adams, G.P.  2019.  New insights of the role of β-NGF in the ovulation mechanism of induced ovulating species.  Reproduction, 157(5): R199-R207.  https://www.doi.org/10.1530/REP-18-0305

  • Adams, G.P., Ratto, M.H., Carrasco, R.A.  2018.  Natural and controlled ovulation in South American camelids.  Animal Reproduction, 15: 996-1002.  https://www.doi.org/10.21451/1984-3143-AR2018-0033

  • Bogle, O.A., Carrasco, R.A., Ratto, M.H., Singh, J., Adams, G.P.  2018.  Source and localization of ovulation-inducing factor/nerve growth factor in male reproductive tissues among mammalian species.  Biology of Reproduction, 99(6): 1194-1204.  https://www.doi.org/10.1093/biolre/ioy149

  • Carrasco, R.A., Singh, J., Adams, G.P.  2018.  Distribution and morphology of gonadotropin-releasing hormone neurons in the hypothalamus of an induced ovulator – The llama (Lama glama).  General and Comparative Endocrinology, 263: 43-50.  https://www.doi.org/10.1016/j.ygcen.2018.04.011

  • Carrasco, R.A., Singh, J., Adams, G.P.  2018.  The relationship between gonadotropin releasing hormone and ovulation inducing factor/nerve growth factor receptors in the hypothalamus of the llama.  Reproductive Biology and Endocrinology, 16(1): 83.  https://www.doi.org/10.1186/s12958-018-0402-6

  • Dias, F.C.F., Khan, M.I.R., Sirard, M.A., Adams, G.P., Singh, J.  2018.  Transcriptome analysis of granulosa cells after conventional vs long FSH-induced superstimulation in cattle.  BMC Genomics, 19(1): 258.  https://www.doi.org/10.1186/s12864-018-4642-9

  • Leonardi, C.E.P., Dias, F.C.F., Adams, G.P., Singh, J.  2018.  Effect of Kisspeptin-10 on plasma luteinizing hormone concentrations and follicular dynamics during the luteal phase in cattle.  Theriogenology, 119: 268-274.  https://www.doi.org/10.1016/j.theriogenology.2018.06.023

  • Palomino, J.M., Jones, L., Vanhanen, T., Mastromonaco, G.F., Busato, R., Adams, G.P.  2018.  Alpaca embryo transfer on a private Canadian farm.  Canadian Veterinary Journal, 59(6): 631-634.

  • Shero, M.R., Bergfelt, D.R., Testa, J.W., Adams, G.P.  2018.  Pairing ultrasonography with endocrinology to elucidate underlying mechanisms of successful pregnancy in the northern fur seal (Callorhinus ursinus).  General and Comparative Endocrinology, 255: 78-89.  https://www.doi.org/10.1016/j.ygcen.2017.10.007

  • Varughese, E.E., Adams, G.P., Leonardi, C.E.P., Malhi, P.S., Babyn, P., Kinloch, M., Singh, J.  2018.  Development of a domestic animal model for endometriosis: Surgical induction in the dog, pigs, and sheep.  Journal of Endometriosis and Pelvic Pain Disorders, 10(2): 95-106.  https://www.doi.org/10.1177/2284026518773942

  • Yapura, M.J., Zwiefelhofer, E.M., Pierson, R.A., Adams, G.P.  2018.  Aromatase inhibitors: A new approach for controlling ovarian function in cattle.  Theriogenology, 112: 18-25.  https://www.doi.org/10.1016/j.theriogenology.2017.08.025

  • Allaway, H.C.M., Chizen, D.R., Adams, G.P., Pierson, R.A.  2017.  Effects of a single 20 mg dose of letrozole on ovarian function post dominant follicle selection: An exploratory randomized controlled trial.  Journal of Ovarian Research, 10(1): 6.  https://www.doi.org/10.1186/s13048-017-0303-x

  • Cervantes, M.P., Palomino, J.M., Anzar, M., Mapletoft, R.J., Mastromonaco, G.F., Adams, G.P.  2017.  In vitro embryo production in wood bison (Bison bison athabascae) using in vivo matured cumulus-oocyte complexes.  Theriogenology, 89: 122-130.  https://www.doi.org/10.1016/j.theriogenology.2016.10.017

  • Cervantes, M.P., Palomino, J.M., Anzar, M., Mapletoft, R.J., Mastromonaco, G.F., Adams, G.P.  2017.  In vitro-production of embryos using immature oocytes collected transvaginally from superstimulated wood bison (Bison bison athabascae).  Theriogenology, 92: 103-110.  https://www.doi.org/10.1016/j.theriogenology.2017.01.017

  • Dadarwal, D., Dias, F.C.F., Adams, G.P., Singh, J.  2017.  Effect of follicular aging on ATP content and mitochondria distribution in bovine oocytes.  Theriogenology, 89: 348-358.  https://www.doi.org/10.1016/j.theriogenology.2016.09.039

  • Palomino, J.M., Cervantes, M.P., Mapletoft, R.J., Woodbury, M.R., Adams, G.P.  2017.  Effect of extending FSH treatment on superovulation and embryo production in wood bison (Bison bison athabascae).  Theriogenology, 95: 18-23.  https://www.doi.org/10.1016/j.theriogenology.2017.02.020

  • Palomino, J.M., Cervantes, M.P., Woodbury, M.R., Mapletoft, R.J., Adams, G.P.  2017.  Effects of eCG and progesterone on superovulation and embryo production in wood bison (Bison bison athabascae).  Animal Reproduction Science, 181: 41-49.  https://www.doi.org/10.1016/j.anireprosci.2017.03.013

  • Silva, M., Ulloa-Leal, C., Valderrama, X.P., Bogle, O.A., Adams, G.P., Ratto, M.H.  2017.  Nerve growth factor from seminal plasma origin (spβ-NGF) increases CL vascularization and level of mRNA expression of steroidogenic enzymes during the early stage of Corpus Luteum development in llamas.  Theriogenology, 103: 69-75.  https://www.doi.org/10.1016/j.theriogenology.2017.07.041

  • Adams, G.P., Ratto, M.H., Silva, M.E., Carrasco, R.A.  2016.  Ovulation-inducing factor (OIF/NGF) in seminal plasma: a review and update.  Reproduction in Domestic Animals, 51: 4-17.  https://www.doi.org/10.1111/rda.12795

  • Carrasco, R., Singh, J., Adams, G.P.  2016.  The dynamics of trkA expression in the bovine ovary are associated with a luteotrophic effect of ovulation-inducing factor/nerve growth factor (OIF/NGF).  Reproductive Biology and Endocrinology, 14(1): 47.  https://www.doi.org/10.1186/s12958-016-0182-9

  • Cervantes, M.P., Palomino, J.M., Anzar, M., Mapletoft, R.J., Adams, G.P.  2016.  In vivo and in vitro maturation of oocytes collected from superstimulated wood bison (Bison bison athabascae) during the anovulatory and ovulatory seasons.  Animal Reproduction Science, 173: 87-96.  https://www.doi.org/10.1016/j.anireprosci.2016.09.001

  • Montgomery, J.E., Wesolowski, M.J., Wolkowski, B., Chibbar, R., Snead, E.C.R., Singh, J., Pettitt, M., Malhi, P.S., Barboza, T., Adams, G.  2016.  Demonstration of synchrotron x-ray phase contrast imaging computed tomography of infiltrative transitional cell carcinoma of the prostatic urethra in a dog.  Journal of Medical Imaging, 3(1): 15504.  https://www.doi.org/10.1117/1.JMI.3.1.015504

  • Palomino, J.M., Cervantes, M.P., McCorkell, R.B., Mapletoft, R.J., Adams, G.P.  2016.  Superovulation in wood bison (Bison bison athabascae): Effects of progesterone, treatment protocol and gonadotropin preparations for the induction of ovulation.  Animal Reproduction Science, 167: 31-39.  https://www.doi.org/10.1016/j.anireprosci.2016.02.001

  • Yapura, M.J., Mapletoft, R.J., Pierson, R.A., Singh, J., Adams, G.P.  2016.  Synchronization of ovulation in cattle with an aromatase inhibitor–based protocol.  Theriogenology, 85(8): 1382-1389.  https://www.doi.org/10.1016/j.theriogenology.2015.12.012

  • Palomino, J.M., Cervantes, M.P., Adams, G.P.  2015.  Inducing ovulation in wood bison (Bison bison athabascae) during the anovulatory season.  Animal Reproduction Science, 163: 18-23.  https://www.doi.org/10.1016/j.anireprosci.2015.09.006

  • Dadarwal, D., Adams, G.P., Hyttel, P., Brogliatti, G.M., Caldwell, S., Singh, J.  2015.  Organelle reorganization in bovine oocytes at different stages of dominant follicle growth and maturation. Reproductive Biology and Endocrinology, 13: 124  https://www.doi.org/10.1186/s12958-015-0122-0

  • Shero, M.R., Adams, G.P., Burns, J.M.  2015.  Field use of ultrasonography to characterize the reproductive tract and early pregnancy in a phocid, the Weddell seal (Leptonychotes weddellii). The Anatomical Record, 298: 1970–1977.  https://www.doi.org/10.1002/ar.23264