Western College of Veterinary Medicine

Research Area(s)

  • Cardiovascular research

Academic Credentials

  • BA, University of Saskatchewan
  • MSc, University of Saskatchewan
  • PhD, University of Saskatchewan

Dr. Hiebert teaches cardiovascular physiology, neurophysiology and haematology at the undergraduate level. She also teaches cardiovascular toxicology and toxicokinetics at the graduate level. She has an active research laboratory with graduate students with training in both in vivo and in vitro methods.

Research Interests

Dr. Hiebert's cardiovascular research includes the pharmacodynamics of orally administered heparins and related polyanions, and damage and protection of endothelial cells. 


Hiebert, L.M., 2017, Proteoglycans and Diabetes, Current Pharmaceutical Design (review) 23, 1-10, DOI: 10.2174/1381612823666170125154915 (In press)

Hiebert, L.M, 2016, Repeated oral or subcutaneous LMWH has similar antithrombotic activity in a rat venous thrombosis model: Antithrombotic activity correlates with heparin on endothelium when orally administered. Journal of Cardiovascular Pharmacology and Therapeutics. 1-9. DOI: 10.1177/1074248416667601

Linda M. Hiebert, Jimin Liu. 2014,  Heparin and Vascular Health in Heparin: Structure, Drug Delivery Applications and Clinical Outcomes Editor Nicole B Wilkinson, Nova Publishers, Hauppauge NY, USA. 41-70. (Invited Book Chapter) 

Linda M. HiebertJuying Han, Anil K. Mandal. 2014, Glycosaminoglycans, Hyperglycemia, and Disease.  Antioxidants & Redox Signaling Doi:10.1089/ars.2013.5695. (Invited Review)

Mala Erickson, Linda M. Hiebert, Anthony P. Carr, Jocelyn D. Stickney, 2014, Effect of oral administration of unfractionated heparin on coagulation parameters in plasma, and urine and fecal heparin levels in the dog. Canadian Journal of Veterinary Research, Vol. 78, No. 3, 193-201.

Juying Han, Linda M. Hiebert, 2013, Alteration of endothelial proteoglycan and heparanase gene expression by high glucose, insulin and heparin. Vascular Pharmacology, 59, No 3-4, 112-118.        

Linda M. Hiebert, Tilly Ping, Sandra Wice, 2011, Repeated doses of oral and subcutaneous        heparins have similar antithrombotic effects in a rat carotid arterial model of thrombosis. Journal of Cardiovascular Pharmacology and Therapeutics. 1-7, DOI:10.1177/1074248411405991

 Mandal AK, Hiebert, L.M. and Khamis,H, 2010, dGlucose is linked to renal function changes in diabetes.  Diabetes Research and Clinical Practice, doi:10.1016/j.diabetes.2010.11.013

 Juying Han, Fuming Zhang, Jin Xie, Robert J Linhardt and Linda M Hiebert, 2009, Changes in cultured endothelial cell glycosaminoglycans under hyperglycemic conditions and the effect of insulin and heparin. Cardiovascular Diabetology 2009, 8:46