Lynn Weber
Associate Dean, Research and Graduate Studies, WCVM | Professor, Department of Veterinary Biomedical SciencesResearch Area(s)
- Environmental, nutritional and toxicological influences on metabolism and the cardiovascular system.
Academic Credentials
- BSc, Pharmacy, University of British Columbia
- PhD, Pharmacology & Toxicology, University of British Columbia
- Post-doctoral Fellow, Smooth Muscle Research Group, University of Calgary
- Post-doctoral Researcher, Zoology, Oklahoma State University
Dr. Weber's teaching is in VBMS 306 (General Pharmacology) covering sections on autonomic, cardiac and diuretic pharmacology and veterinary nutrition in VLAC 315. She contributes sections to several other undergraduate and graduate courses in cardiovascular physiology and toxicology.
Research Interests
Dr. Weber's research focus is examining how environmental, nutritional and toxicological factors influence metabolism and the cardiovascular system. Her research includes topics in a wide variety of species, from fish to rodents, pigs, dogs and cats. These are her current or recent research projects:
- Role of taurine deficiency and amino acid nutritional physiology in canine dilated cardiomyopathy.
- How glycemic index, obesity and diabetes negatively interact to negatively affect cardiovascular health.
The Weber lab is committed to equity, diversity and inclusion by creating a supportive, team work driven environment. We welcome students from all backgrounds to create diversity in viewpoints and are flexible to accomodate differing needs. We use this principal as we work toward a common goal of helping to keep ourselves and our animals safe and healthy.
Weber lab lunch Feb 2020: (L to R) Chloe Quilliam, Bright Boamah, Lynn Weber, Priscila Curso-Almeida, Luciana Guimaraes-Reis, Tressa Morris
Publications
Boamah, B., Siciliano, S., Hogan, N., Hecker, M., Hanson, M., Campbell, P., Peters, R., Al-Dissi, A., Weber, L.P. 2024. Target organ toxicity in Sprague Dawley rats following oral exposure to complex groundwater mixture: Assessment of dose-response relationships using histopathological and biochemical alterations. Regulatory Toxicology & Pharmacology 154: 105744. DOI:org/10.1016/j.yrtph.2024.105744
Gasque-Belz, L., Carriere, K., Humeniuk, B., Park, B., Colville, C., Siciliano, S.D., Hogan, N., Weber, L., Campbell, P., Peters, R., Hecker, M., Hanson, M. 2024. Application of a novel approach method to assess the hazard of complex legacy contaminated groundwater mixtures on fathead minnows in outdoor mesocosms. Science of the Total Environment 953:176081. org/10.1016/j.scitotenv.2024.176081.
Alehashem M., Alcaraz A.J., Hogan N., Weber L., Siciliano S.D., Hecker M. 2024. Linking pesticide exposure to neurodegenerative diseases: An in vitro investigation with human neuroblastoma cells. Science of the Total Environment, 933: 173041. DOI: 1016/j.scitotenv.2024.173041.
Boamah, B., Morse, C., Siciliano, S., Hogan, N., Hecker, M., Hanson, M., Campbell, P., Peters, R., Al-Dissi, A., Olver, T.D., Weber, L.P. 2024. Impaired memory in Sprague-Dawley rats exposed to complex groundwater mixtures of contaminants is associated with reduced cranial blood flow and hippocampal neurotoxicity. Neurotoxicology 103: 288. DOI:org/10.1016/j.neuro.2024.07.005.
Gheisary, Z., Hoja, I., Liu, J., Papagerakis, P., Weber, L.P., Fenton, M., Katselis, G.S., Lieffers, J.R.L., Papagerakis, S. 2024. Association of sleep quality, general, mental, and oral health with lifestyle traits (dietary intake, smoking status) in arthritis: A cross-sectional study from the 2017-2018 Canadian Community Health Survey (CCHS). Nutrients 16: 2091. org/10.3390/nu16132091.
Gasque-Belz, L., Park, B., Siciliano, S.D., Hogan, N., Weber, L., Campbell, P., Peters, R., Hanson, M., Hecker, M. 2024. Characterization of adverse outcomes from legacy-contaminated groundwater exposure to early life stages of fathead minnows. Archives of Environmental Contamination & Toxicology June 13 2024. DOI:org/10.1007/s00244-024-01069-7.
Ren, Y., Bokshowan , E., Warkentin, T.D., Weber , L.P, Ai, Y. 2024. Effects of rosemary extract addition on starch bioavailability and antioxidant properties of extruded pet foods. Animal Feed Science & Technology 313: 116005. DOI:org/10.1016/j.anifeedsci.2024.116005.
Boamah, B., Siciliano, S., Hogan, N., Hecker, M., Hanson, M., Campbell, P., Peters, R., Al-Dissi, A., Weber, L.P. 2024. Time-course of oral toxicity to contaminated groundwater in male Sprague Dawley rats. Toxicology Reports 12:584-593. org/10.1016/j.toxrep.2024.05.002.
Alehashem, M., Alcaraz, A.J., Hogan, N., Weber, L., Siciliano, S.D., Hecker, M. 2024. In vitro characterization of the toxicity of four organochlorine pesticides and three registered herbicides in human neuroblastoma (SH-SY5Y) cells. Science of the Total Environment, 933: 173041. org/10.1016/j.scitotenv.2024.173041.
Curso-Almeida, P., Subramaniam, M., Gallagher, A., Adolphe, J.A., Drew, M.D., Loewen, M.E., Weber, L.P. Determining the effects of C. utilis-fermented pea starch vs. unfermented pea starch, alone or in whole diets, on palatability and glycemic response in dogs and cats. Journal of Animal Physiology & Animal Nutrition 108(4): 934-949. DOI.org/10.1111/jpn.13940.
Gasque-Belz, L., Raes, K., Park, B., Colville, C., Siciliano, S.D., Hogan, N., Weber, L., Campbell, P., Peters, R., Hanson, M., Hecker, M. 2024. Hazard assessment of complex legacy-contaminated groundwater mixtures using a novel approach method in adult Fathead Minnows under laboratory conditions. Journal of Hazardous Material 465:133299. DOI:org/10.1016/j.jhazmat.2023.133299.