Research Area(s)
- Virology, virus-host interactions, signal transduction, regulation of gene transcription, translational control, post-translational modification
Academic Credentials
- BSc, Nankai University, Tianjin, China
- MSc, Nankai University, Tianjin, China
- PhD., Justus Liebig University, Giessen, Germany
Research Interests
Publications
Zhu J, Brownlie R, Liu Q, Babiuk LA, Potter A, Mutwiri GK. 2009. "Characterization of bovine Toll-like receptor 8: Ligand specificity, signaling essential sites and dimerization." Molecular Immunology. 978-90.
Oem JK,Jackel-Cram C, Zhou Y, Shimano H, Babiuk LA, Liu Q. 2008. "Activation of sterol regulatory element binding protein-1c and fatty acid synthase transcription by hepatitis C virus non-structural protein-2." Journal of General Virology. 89:1225-1230.
Oem JK, Jackel-Cram C, Li Y, Kang H-N, Zhou Y, Babiuk LA, Liu Q. 2008. "Hepatitis C virus non-structural protein-2 activates interleukin-8 transcription through NF-kappaB." Archives of Virology. 153:293-301.
Li Y, Anderson DH, Liu Q, Zhou Y. 2008. "Mechanism of influenza A virus NS1 protein interaction with the p85beta, but Not the p85alpha, subunit of phosphatidylinositol 3-kinase (PI3K) and up-regulation of PI3K activity." Journal of Biological Chemistry. 23397-409.
Oem JK, Xiang Z, Zhou Y, Babiuk LA, Liu Q. 2007. "Utilization of RNA polymerase I promoter and terminator sequences to develop a DNA transfection system for the study of hepatitis C virus internal ribosomal entry site-dependent translation." Journal of Clinical Virology. 40:55-59.
Jackel-Cram C, Babiuk LA, Liu Q. 2007. "Up-regulation of fatty acid synthase promoter by hepatitis C virus core protein: genotype 3a core has a stronger effect than genotype 1b core." Journal of Hepatology. 46:999-1008. Highlighted by editorials: “Hepatitis C virus: The viral way to fatty liver”, Clément S, Negro F. Journal of Hepatology. 46:985-987, 2007; “Fatty liver in chronic hepatitis C infection: unravelling the mechanisms”, Oben JA, Paulon E. Gut. 56:1186-8, 2007.
Shin, Y. K. Liu, Q. Tikoo, S. K. Babiuk, L. A. Zhou, Y. (2007), Effect of the phosphatidylinositol 3-kinase/Akt pathway on influenza A virus propagation, J Gen Virol, 942-50.
Shin, Y. K. Li, Y. Liu, Q. Anderson, D. H. Babiuk, L. A. Zhou, Y. (2007), SH3 binding motif 1 in influenza A virus NS1 protein is essential for PI3K/Akt signalling pathway activation, J Virol.
Shin, Y. K. Liu, Q. Tikoo, S. K. Babiuk, L. A. Zhou, Y. (2007), Influenza A virus NS1 protein activates the phosphatidylinositol 3-kinase (PI3K)/Akt pathway by direct interaction with the p85 subunit of PI3K, J Gen Virol, 13-8.
Oem, J. K. Xiang, Z. Zhou, Y. Babiuk, L. A. Liu, Q. (2007), Utilization of RNA polymerase I promoter and terminator sequences to develop a DNA transfection system for the study of hepatitis C virus internal ribosomal entry site-dependent translation, J Clin Virol, 55-9.
Li, Y. P. Kang, H. N. Babiuk, L. A. Liu, Q. (2006), Elicitation of strong immune responses by a DNA vaccine expressing a secreted form of hepatitis C virus envelope protein E2 in murine and porcine animal models, World J Gastroenterol, 7126-35.
Zakhartchouk, A. N. Liu, Q. Petric, M. Babiuk, L. A. (2005), Augmentation of immune responses to SARS coronavirus by a combination of DNA and whole killed virus vaccines, Vaccine, 4385-91