Research Area(s)
- Molecular biology, pathogenesis and vaccine development of influenza virus
Academic Credentials
- MSc, Nankai University, Tianjin, China
- PhD, Justus-Liebieg University, Giessen, Germany
- Post-Doctoral Fellow, VIDO, University of Saskatchewan
- Post-Doctoral Felow, Faculty of Medicine, University of Calgary
Dr. Zhou is a Scientist and Project Leader (influenza) at the Vaccine and Infectious Disease Organization (VIDO).
Publications
Masic, A. Booth, J. S. Mutwiri, G. K. Babiuk, L. A. Zhou, Y. (2009), Elastase-dependent live attenuated swine influenza A viruses are immunogenic and confer protection against swine influenza A virus infection in pigs, J Virol, 10198-210
Masic A, Babiuk LA, Zhou Y. 2009. "Reverse genetics generated elastase-dependent swine influenza viruses are attenuated in pigs." Journal of General Virology. 90: 375-385.
Oem, J. K. Jackel-Cram, C. Li, Y. P. Zhou, Y. Zhong, J. Shimano, H. Babiuk, L. A. Liu, Q. (2008), Activation of sterol regulatory element-binding protein 1c and fatty acid synthase transcription by hepatitis C virus non-structural protein 2, J Gen Virol, 1225-30.
Oem, J. K. Jackel-Cram, C. Li, Y. P. Kang, H. N. Zhou, Y. Babiuk, L. A. Liu, Q. (2008), Hepatitis C virus non-structural protein-2 activates CXCL-8 transcription through NF-kappaB, Arch Virol, 293-301.
Li Y, Anderson DH, Liu Q, Zhou Y. 2008. "Mechanism of influenza A virus NS1 protein interaction with the p85beta , but not the p85alpha, subunit of PI3K and upregulation of PI3K activity." Journal of Biological Chemistry. 283(34):23397-409.
Zhou, Y. Ficzycz, A. Tikoo, S. K. (2007), Porcine adenovirus type 3 E1B large protein downregulates the induction of IL-8, Virol J, 60.
Shin YK, Li Q, Anderson DH, Babiuk LA, Zhou Y. 2007. "SH3 binding motif 1 in influenza A virus NS1 protein is essential for PI3K/Akt signaling pathway activation." Journal of Virology. 81(23):12730-9.
Shin YK, Liu Q, Tikoo SK, Babiuk LA, Zhou Y. "Effect of PI3K/Akt pathway on influenza A virus propagation." 2007. Journal of General Virology. 88:942-950.
Shin YK, Liu Q, Tikoo SK, Babiuk LA, Zhou Y. 2007. "Influenza virus activates PI3K /Akt pathway by direct interaction of NS1 with p85 subunit of PI3K." Journal of General Virology. 88:13-8.
Oem, J. K. Xiang, Z. Zhou, Y. Babiuk, L. A. Liu, Q. (2007), Utilization of RNA polymerase I promoter and terminator sequences to develop a DNA transfection system for the study of hepatitis C virus internal ribosomal entry site-dependent translation, J Clin Virol, 55-9.