Throughout its history, WCVM researchers have used models of anatomy, physiology, disease or drug therapies to make valuable advances in animal and human health. For example, WCVM faculty members have developed translational research models in areas such as reproduction where bovine models have helped scientists learn more about ovarian function and follicular dynamics in both animals and humans. Researchers are also learning more about the manipulation of spermatogenesis for human therapies through the use of animal models.
In the area of neurophysiology, rat models are helping research teams learn more about the effects of central nervous system disease or injury on the sensorimotor behaviour of humans as well as animals. Testing the effectiveness of antithrombotic drugs, such as heparin, in dogs is helping scientists learn more about their pharmocodynamics and use in humans.
In the area of environmental toxicology, swine, fish and canine models are helping researchers learn more about the effect of environmental toxicants on the cardiovascular system. Translational research models are also highly effective in the areas of ophthalmology and oncology where human and veterinary scientists can equally gain fresh perspectives on the pathogenesis of disease as well as treatment, early detection and prevention.