The WCVM has been involved in investigations focused on wildlife health since the mid-1960s. To gain support for these projects, the college initiated its Wildlife Health Fund in 1981 to encourage and support applied research and training in the health and diseases of free-ranging wildlife. The WCVM was also instrumental in creating the Canadian Wildlife Health Cooperative (CWHC) — a national organization that applies the veterinary medical sciences to wildlife conservation and management in Canada through the country's veterinary colleges.

The WCVM was also instrumental in creating the Canadian Wildlife Health Cooperative (CWHC) — a national organization that applies the veterinary medical sciences to wildlife conservation and management in Canada through the country's veterinary colleges.

WCVM faculty members from a variety of disciplines — pathology, physiology, toxicology, epidemiology, medicine, parasitology and anesthesia — are involved in wildlife health research and education at the veterinary college. The college's research teams have conducted studies on a variety of topics including stress physiology, aquatic and wildlife toxicology, environmental effects on the developmental and reproductive processes in vertebrates, epidemiological investigations of non-infectious and infectious diseases, the ecology of parasites, and the effect of environmental contaminants on the health of wildlife.

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