Cryptosporidium spp. are gastrointestinal coccidians (although the taxonomy is controversial) of a wide range of vertebrates (mammals, birds, amphibians, reptiles, and fish). Surveys from several locations around the world based on fecal examination for Cryptosporidium oocysts have demonstrated a prevalence of up to 40 per cent in dogs and cats.
Free-living amoebae are protozoa that normally live in the environment and only occasionally infect human or animal hosts. Acanthamoeba spp. and Naegleria fowleri are the most commonly seen species, both causing central nervous system infection and disease.
Species of the flagellate protozoan Leishmania infect people, domestic dogs and an array of free-ranging mammals in South and Central America, southern Europe, the Middle East, Africa, Asia, and most recently dogs in North America.
Neospora caninum is a protozoan parasite, closely related and in several respects similar to Toxoplasma gondii, that is a major cause of abortion in cattle around the world and an occasional cause of neurological disease in young calves, dogs and other mammalian hosts.